Light switch for life: Controlling molecular droplets with UV

Biomolecular condensates are tiny, droplet-like structures made up of molecules that help organize key processes in living organisms. Because they are so small and constantly changing, it has been difficult for scientists ...

Soil bacteria break down toxic chemicals in the environment

Many aromatic compounds, such as phenols, cresols and styrenes, are toxic to organisms and harmful to the environment. They can accumulate as a result of industrial processes and harm ecosystems. Soil bacteria can help to ...

Understanding protein motion could greatly aid new drug design

For many people, "protein" is the key element of a food order. However, beyond the preferred choice of meats or plant-based alternatives, proteins encompass a large class of complex biomolecules whose chemical structure is ...

Designing proteins by their motion, not just their shape

Proteins are far more than nutrients we track on a food label. Present in every cell of our bodies, they work like nature's molecular machines. They walk, stretch, bend, and flex to do their jobs, pumping blood, fighting ...

DNA shape explains crucial gene-therapy challenges

CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a precision tool, but is not perfect, and misplaced DNA edits can compromise safety and efficacy, ...

RNA-guided CRISPR system activates gene expression

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR gene-editing ...

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