News tagged with transgenic mice

Researchers demonstrate green tea is effective in treating genetic disorder and types of tumors

A compound found in green tea shows great promise for the development of drugs to treat two types of tumors and a deadly congenital disease. The discovery is the result of research led by Principal Investigator, ...

Chemistry / Biochemistry

created Aug 15, 2011 | popularity 4.8 / 5 (5) | comments 3 | with audio podcast

Research offers clue to halt Huntington's disease

(PhysOrg.com) -- Surprising findings from a study into the brains of transgenic mice carrying the Huntington's disease mutation could pave the way for treatments which delay the onset and progression of this devastating genetic ...

Medicine & Health / Medical research

created Mar 25, 2011 | popularity 3.5 / 5 (2) | comments 0 | with audio podcast

Transcription factor clears protein clumps in Huntington's mice models

Over expressing a transcription factor that promotes the increase in number of mitochondria greatly improves the neurological function of transgenic mice models for Huntington's disease (HD), researchers today told the American ...

Biology / Cell & Microbiology

created Dec 14, 2010 | popularity not rated yet | comments 0

Gladstone scientists identify process by which Alzheimer's disease creeps through the brain

Scientists at the Gladstone Institute of Neurological Disease (GIND) have offered new information about the events that underlie the "spread" of Alzheimer's disease (AD) throughout the brain. The research, published in the ...

Medicine & Health / Medical research

created Nov 03, 2010 | popularity 5 / 5 (1) | comments 0

Progress being made in stem-cell therapy, scientist says

For the past two decades, scientists have been trying to fulfill the promise that stem-cell therapy holds for treating diseases such Parkinson’s, Alzheimer’s and many others. Their ultimate goal is to be able ...

Biology / Biotechnology

created Sep 30, 2010 | popularity 5 / 5 (1) | comments 0

Getting off tract: Polyglutamine disease involves other regions of protein

Many genes code for proteins that have a "polyglutamine tract," several glutamine amino acid residues in a row. Nine inherited neurodegenerative diseases, including Huntington's disease and spinocerebellar ataxia type 1 (SCA1), ...

Medicine & Health / Neuroscience

created Sep 22, 2010 | popularity not rated yet | comments 0

Scientists discover new protein that gets to the roots of obesity and osteoporosis

Here's good news for anyone trying to lose weight or has osteoporosis: Scientists from Maine are on the trail of a weight loss drug that may revolutionize how we treat these two conditions. In a new research report published ...

Medicine & Health / Medical research

created Aug 31, 2010 | popularity 5 / 5 (3) | comments 0

Sense of smell holds the key to diagnosis and treatment in early stage Parkinson's disease

A fast, simple and non invasive test of the ability to smell may be an important tool to screen people who are likely to develop Parkinson's disease (PD), in which motor symptoms only become evident at a later stage of the ...

Medicine & Health / Diseases, Conditions, Syndromes

created Jun 11, 2010 | popularity 3.4 / 5 (5) | comments 0

Researchers embark on work to control the prion epidemic affecting deer in the USA

Spanish researchers at the Centre for Cooperative Research in Bioscience, CIC bioGUNE, in collaboration with the University of Kentucky (USA), have discovered a new way to control the stability of certain types of prions ...

Biology / Other

created May 19, 2010 | popularity 4 / 5 (2) | comments 0

Promising strategy for treatment of lung cancer

A research team at the Sahlgrenska Academy at the University of Gothenburg, Sweden, has shown in a study that two closely related enzymes could be targets for the treatment of lung cancer. The discovery was made when the ...

Medicine & Health / Cancer

created Mar 29, 2010 | popularity not rated yet | comments 0

German researchers develop new tool to investigate ion channels

Neurotoxins from cone snails and spiders help neurobiologists Sebastian Auer, Annika S. Stürzebecher and Dr. Ines Ibañez-Tallon of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, ...

Chemistry / Biochemistry

created Feb 10, 2010 | popularity not rated yet | comments 0

Synergistic interaction enhances pathogenesis of Parkinson's disease

Scientists have identified a synergistic interaction that disrupts normal intracellular transport mechanisms and leads to the accumulation of neuron-damaging clumps of protein associated with Parkinson's disease (PD), a neurodegenerative ...

Electronics /

created Dec 23, 2009 | popularity not rated yet | comments 0

Low-density lipoprotein receptor reduces damage in Alzheimer's brain

The low-density lipoprotein receptor (LDLR) has received a lot of attention because of its connection with coronary heart disease and atherosclerosis, but now it appears as if it may have a beneficial influence in degenerative ...

Medicine & Health / Neuroscience

created Dec 09, 2009 | popularity 5 / 5 (1) | comments 0

Researchers create first transgenic prairie voles

Researchers at the Yerkes National Primate Research Center, Emory University, have successfully generated the first transgenic prairie voles, an important step toward unlocking the genetic secrets of pair bonding. The future ...

Biology / Biotechnology

created Dec 01, 2009 | popularity 3 / 5 (1) | comments 0

Novel mouse gene reduces major pathologies associated with Alzheimer's disease

A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD). The research, published by Cell Press in the November 12 issue ...

Medicine & Health / Neuroscience

created Nov 11, 2009 | popularity 3.8 / 5 (4) | comments 0