Researchers at ETH Zurich are decoding the structure of the large ribosomal subunit of the mitochondria at an atomic level, thereby providing insight into the molecular architecture of this ribosome with implications for ...
Biochemistry
Oct 8, 2014
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The so-called central dogma of molecular biology—that DNA makes RNA which makes protein—has long provided a simplified explanation for how genetic information is deciphered and translated in living organisms.
Cell & Microbiology
Sep 15, 2014
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Working with a gene that plays a critical role in HIV infection, University of Maryland researchers have discovered that some human genes have an alternate set of operating instructions written into their protein-making machinery. ...
Cell & Microbiology
Jul 9, 2014
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The molecular machine that makes essential components of ribosomes – the cell's protein factories – is like a Swiss-army knife, researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and ...
Cell & Microbiology
Oct 24, 2013
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(Phys.org) —Streptomycin was the first antibiotic developed to treat tuberculosis yet until recently, scientists did not completely understand how it works at the molecular level. They knew that streptomycin blocks a critical ...
Biochemistry
Sep 6, 2013
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An analysis of enzymes that load amino acids onto transfer RNAs—an operation at the heart of protein translation—offers new insights into the evolutionary origins of the modern genetic code, researchers report. Their ...
Biotechnology
Aug 26, 2013
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A new study shows how complex biochemical transformations may have been possible under conditions that existed when life began on the early Earth. The study shows that RNA is capable of catalyzing electron transfer under ...
Biochemistry
May 19, 2013
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The enzyme needed to introduce the key micronutrient selenium into bacteria looks something like a space station with 10 different docking stations.
Biochemistry
Apr 5, 2013
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For the past several years, Min Guo, an assistant professor at The Scripps Research Institute, has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process ...
Cell & Microbiology
Nov 15, 2012
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(Phys.org)—Bacteria may be simple creatures, but unlike "higher" organisms they have a neat evolutionary trick. When the going gets tough, they can simply pick up and incorporate a loose bit of genetic material from their ...
Cell & Microbiology
Aug 31, 2012
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