Efficient synthesis of quinine paves way for malarial drug development
Malaria is one of the world's "big three" infectious diseases. In 2020 alone, it infected roughly 240,000 million people and caused 630,000 deaths worldwide.
Malaria is one of the world's "big three" infectious diseases. In 2020 alone, it infected roughly 240,000 million people and caused 630,000 deaths worldwide.
Biochemistry
Dec 8, 2022
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46
New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...
Biochemistry
Dec 5, 2022
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15
In recent years, electrocatalysis has swiftly established its dominance in organic synthesis owing to its high efficiency and low contamination. However, without developed methods for controlling regio- and stereochemistry, ...
Analytical Chemistry
Dec 2, 2022
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5
The chemical industry faces the challenge of replacing fossil-based building blocks with green alternatives. Biomass is an interesting source of carbon-based molecules. It is also underused because some 25 percent of all ...
Biochemistry
Nov 29, 2022
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33
Researchers at CiTOS—Center for Integrated Technology and Organic Synthesis (University of Liège, BE) led by Jean-Christophe Monbaliu have devised an on-demand flow platform for the generation of anhydrous dinitrogen trioxide ...
Analytical Chemistry
Nov 28, 2022
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75
Urea (CO(NH2)2) has been applied both in agricultural and pharmaceutical field. The widely used Bosch-Meiser process has high energy consumption and CO2 emission. Therefore, it is imperative to explore energy-saving and economical ...
Analytical Chemistry
Nov 25, 2022
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7
Various chemical products, such as polymers and pharmaceutical intermediates, are currently synthesized with phosgene as their precursor or raw material. However, phosgene is highly toxic and this usage poses safety risks. ...
Analytical Chemistry
Nov 22, 2022
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In a paper just published in ACS Catalysis, the Biocatalysis research group at the University of Amsterdam's Van 't Hoff Institute for Molecular Synthesis presents a versatile method for the synthesis of primary, secondary, ...
Biochemistry
Nov 16, 2022
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48
Layered double hydroxides (LDHs) have a unique structure and many benefits, which have led to them being widely used in fields such as catalysis, environmental management and medical applications. Typically, soluble metal ...
Materials Science
Nov 15, 2022
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5
Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to encode specific proteins; the ...
Bio & Medicine
Nov 10, 2022
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