Scientists identify class of binding molecules that can be used for targeted protein degradation
In the battle against cancer and other diseases, scientists are developing molecular weapons that can be used to stop uncontrollable cell growth.
In the battle against cancer and other diseases, scientists are developing molecular weapons that can be used to stop uncontrollable cell growth.
Biochemistry
Apr 3, 2024
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The nematode worm C. elegans will stay away from dangerous bacteria in its environment when exposed to certain bacterial RNAs—and can transmit that learned behavior to future generations. A team led by Coleen Murphy at ...
Plants & Animals
Mar 28, 2024
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Accidents happen every day, and if you drop your smartwatch, or it gets hit really hard, the device probably won't work anymore. But now, researchers report on a soft, flexible material with "adaptive durability," meaning ...
Polymers
Mar 20, 2024
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Lignin, a complex organic polymer, is one of the main components of wood, providing structural support and rigidity to make trees strong enough to withstand the elements. When transforming wood into paper, lignin is a key ...
Polymers
Mar 18, 2024
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117
Researchers studying the role of proteins in health and disease use experimental tools that inactivate proteins, destroy them, or prevent them from being made in cells. In one approach, they mark targeted proteins with "destroy ...
Biotechnology
Mar 15, 2024
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In the wake of the COVID-19 pandemic, scientists have been racing to develop effective treatments and preventatives against the virus. A recent scientific breakthrough has emerged from the work of researchers aiming to combat ...
Biotechnology
Mar 14, 2024
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Researchers have unveiled the extraordinary behavior of weakly-bound three-atomic molecules, defying conventional understanding of quantum mechanics. In a study recently published in Nature Communications, a team of scientists ...
Quantum Physics
Mar 14, 2024
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David Baker's group at the University of Washington, Seattle, U.S., have developed a novel deep learning method, RoseTTAFold All-Atom (RFAA), for prediction and design of complexes of proteins, small molecules, and nucleic ...
Biotechnology
Mar 11, 2024
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When a child falls off her bike and scrapes her knee, skin stem cells rush to the rescue, growing new epidermis to cover the wound. But only some of the stem cells that will ultimately patch her up are normally dedicated ...
Cell & Microbiology
Mar 7, 2024
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114
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs.
Biochemistry
Mar 7, 2024
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