News tagged with small molecules

Tiny roundworm points to big promise

Two related studies from Northwestern University offer new strategies for tackling the challenges of preventing and treating diseases of protein folding, such as Alzheimer's, Parkinson's and Huntington's diseases, amyotrophic ...

Jan 06, 2012 4.8 / 5 (4) 1 | with audio podcast

Hitting moving RNA drug targets

By accounting for the floppy, fickle nature of RNA, researchers at the University of Michigan and the University of California, Irvine have developed a new way to search for drugs that target this important molecule. Their ...

Jun 26, 2011 5 / 5 (2) 0 | with audio podcast

Searching for purpose in proteins

As scientists continue to acquire immense amounts of genomic and biochemical data from various organisms, they routinely find themselves confronted by proteins of known structure but enigmatic function—and ...

Oct 29, 2010 5 / 5 (1) 0

Small molecules block cancer gene

Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared the structure of the cancer-causing ...

Mar 10, 2009 5 / 5 (1) 1