In a study that could lead to new therapeutic targets for patients with the cystic fibrosis, a research team from the University of California, San Diego School of Medicine has identified a defective signaling pathway that ...
Feb 14, 2010
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In a study to be published this week, a research team is challenging a prevailing belief about the behavior of a human protein linked to the formation of cancer, possibly breathing new life into the search for therapies that ...
Jan 25, 2010
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By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer.
Jan 21, 2010
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(PhysOrg.com) -- A new study provides crucial details that promise to help researchers better understand, and perhaps fine-tune with drugs, one of the most important signaling mechanisms in human cells, according to a study ...
Dec 03, 2009
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Two signaling pathways essential to normal human development - the Wnt/Wingless (Wnt) and epidermal growth factor receptor (EGFR) pathways - interact in ways that can promote tumor cell invasion and metastasis, researchers ...
Nov 25, 2009
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Breathing carbon dioxide can trigger panic attacks, but the biological reason for this effect has not been understood. A new study by University of Iowa researchers shows that carbon dioxide increases brain acidity, which ...
Nov 25, 2009
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Targeting the normal cells that surround cancer cells within and around a tumor is a strategy that could greatly increase the effectiveness of traditional anti-cancer treatments, say researchers at The Wistar Institute.
Nov 16, 2009
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When it comes to plants' innate immunity, like many of the dances of life, it takes two to tango. A receptor molecule in the plant pairs up with a specific molecule on the invading bacteria and, presto, the immune system ...
Nov 05, 2009
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In mice that are missing a protein found only in the brain, neural signals "go crazy," leaving the animals with epileptic seizures from a young age, researchers have found. The report in the September 18th Cell, a Cell P ...
Sep 17, 2009
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Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...
Aug 06, 2009
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(PhysOrg.com) -- University of Arkansas researchers have characterized a membrane receptor protein and its binding mechanism from chloroplasts in plants and determined that it shares a commonly shaped binding ...
Jun 02, 2009
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A team of neuroscientists at Cold Spring Harbor Laboratory (CSHL) has demonstrated the mechanism by which a signaling protein found throughout the brain controls the maturation and strength of excitatory synapses, the tiny ...
Jun 01, 2009
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Sections of proteins previously thought to be disordered may in fact have an unexpected biological role - providing certain proteins room to move -- according to a study published by researchers at Fox Chase Cancer Center ...
May 26, 2009
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Several bacterial pathogens use toxins to manipulate human host cells, ultimately disturbing cellular signal transduction. Until now, however, scientists have been able to track down only a few of the proteins that interact ...
Apr 22, 2009
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When cells undergo potentially catastrophic damage, for example as a result of exposure to ionizing radiation, they must make a decision: either to fix the damage or program themselves for death, a process called apoptosis.
Apr 10, 2009
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