Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired. In particular, mRNA therapeutics hold the potential for application to vaccine therapy ...
Molecular & Computational biology
Jul 16, 2020
0
59
Researchers at the University of Tasmania's Menzies Institute for Medical Research and the School of Medicine have added an arsenal of new tools to their repertoire for fighting the insidious devil facial tumor disease.
Veterinary medicine
Jul 2, 2020
0
31
It is no secret that DNA, in the form of chromosomes, is the building block of life. Incorrect distribution of chromosomes during cell division can have disastrous consequences. Unbalanced chromosome copy, or aneuploidy, ...
Cell & Microbiology
Jun 24, 2020
0
114
The cytoskeleton is a permanent construction site consisting of protein filaments that are continually lengthening and shortening in a dynamic process. Through these remodeling processes, the cell can change its shape and ...
Cell & Microbiology
Mar 24, 2020
0
33
Researchers have developed a process that could sharply reduce the work involved in computational protein design, according to a study in Proceedings of the National Academy of Sciences.
Biochemistry
Feb 27, 2020
0
203
When the machinery that guides the transition of stem cells to somatic cells doesn't shut down properly, cells can become cancerous. Identifying the mechanisms that impede those processes would offer scientists a target for ...
Cell & Microbiology
Feb 11, 2020
0
111
Medicines such as insulin for diabetes and clotting factors for hemophilia are hard to synthesize in the lab. Such drugs are based on therapeutic proteins, so scientists have engineered bacteria into tiny protein-making factories. ...
Molecular & Computational biology
Dec 18, 2019
1
190
Researchers at the EMBL's European Bioinformatics Institute (EMBL-EBI) have created the largest reference phosphoproteome to date of almost 120,000 human phosphosites. To identify those most likely to be critical, they used ...
Biotechnology
Dec 11, 2019
0
73
At the University of Copenhagen, researchers have discovered how some types of proteins stabilize damaged DNA and thereby preserve DNA function and integrity. This new finding also explains why people with inborn or acquired ...
Molecular & Computational biology
Oct 28, 2019
0
45
Scientists at the University of Groningen have constructed synthetic vesicles in which ATP, the main energy carrier in living cells, is produced. The vesicles use the ATP to maintain their volume and their ionic strength ...
Biotechnology
Sep 18, 2019
0
994
