A massive effort to map the precise binding locations of over 400 different kinds of proteins on the yeast genome has produced the most thorough and high-resolution map of chromosome architecture and gene regulation to date. ...
Biotechnology
Mar 10, 2021
0
141
To date, much has been stated about the promise of quantum computing for myriad of applications but there have been few examples of a quantum advantage for real-world problems of practical interest. This might change with ...
Quantum Physics
Feb 27, 2018
0
529
Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins ...
Biochemistry
Apr 5, 2017
0
109
Berkeley Lab and UC Berkeley researchers have discovered that the transcription factor protein TFIID coexists in two distinct structural states, a key to genetic expression and TFIID's ability to initiate the process by which ...
Cell & Microbiology
Jan 17, 2013
0
0
In Alzheimer's disease, brain neurons become clogged with tangled proteins. Scientists suspect these tangles arise partly due to malfunctions in a little-known regulatory system within cells. Now, researchers have dramatically ...
Biochemistry
Apr 16, 2012
1
0
Single-celled organisms, such as bacteria and archaea, have developed many ways to communicate with each other. For example, they might use tiny so-called extracellular vesicles (EVs)—membrane-enveloped packages smaller ...
Cell & Microbiology
Feb 27, 2024
0
7
Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without incurring damage. In mice, ...
Cell & Microbiology
Feb 20, 2024
0
70
Investigators from the laboratory of Ali Shilatifard, Ph.D., the Robert Francis Furchgott Professor and chair of Biochemistry and Molecular Genetics, have discovered a new repeat gene cluster sequence that is exclusively ...
Evolution
Nov 24, 2023
0
260
DNA and RNA, the two main types of nucleic acid and the building blocks of life, are susceptible to environmental stimuli, which can cause them to deform, bend or twist. These deformations can significantly affect gene regulation ...
Molecular & Computational biology
Aug 24, 2023
0
202
In multicellular organisms, all cells of an individual normally contain the same genetic information and cell differentiation is achieved through regulation of gene expression. There are exceptions, however, where, instead ...
Evolution
Aug 9, 2023
0
37
