Researchers at Baylor College of Medicine and collaborating institutions report in the journal Nature Communications how a mutation in the enzyme SKD3 can cause a form of a genetic disease known as 3-methylglutaconic aciduria ...
Cell & Microbiology
Apr 11, 2023
0
18
The Allain (IBC), Gossert (BNSP) and Leitner (IMSB) groups investigated the druggability of the SARS-CoV-2 Nucleocapsid protein RNA interactions by a hybrid structure determination approach, which led to the identification ...
Molecular & Computational biology
Apr 3, 2023
0
1
CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital have used a next-generation protein degradation technology to study ...
Biotechnology
Jan 25, 2023
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22
Some of the toughest challenges in treating disease are presented by "undruggable" proteins whose structures and roles in disease are known but are seemingly unable to be targeted by drugs that will bind to them. Researchers ...
Molecular & Computational biology
Nov 21, 2022
0
33
Researchers from Quantum-Si have published an article in Science that showcases how single-molecule protein sequencing via semiconductor chip and Time Domain Sequencing technologies will transform life science and biomedical ...
Biotechnology
Oct 13, 2022
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50
Joining forces with the Ciaudo (IMHS) and Hall (IPW, D-CHAB) labs, the Allain group (IBC) gained structural insights into the unusual mode of RNA recognition by the Dead End protein complemented by biochemical and cellular ...
Cell & Microbiology
Oct 11, 2022
0
11
One of the fascinating aspects of scientific research is certainly the serendipity that comes with it, which is something the team of Prof. Alain Vanderplasschen, virologist and immunologist at the FARAH (Faculty of Veterinary ...
Cell & Microbiology
Sep 23, 2022
0
2
Researchers at KI and SLU have discovered that spider silk proteins can be fused to biologically active proteins and be converted into a gel at body temperature. One of the goals is to develop an injectable protein solution ...
Biochemistry
Aug 15, 2022
0
45
A team led by UT Southwestern researchers has identified how SARS-CoV-2, the virus that causes COVID-19, builds a structure called the RNA cap that's critical for successful viral replication. The finding, published in Nature, ...
Molecular & Computational biology
Aug 10, 2022
0
92
Johns Hopkins Medicine scientists report they have probed the atomic structure of proteins to add to evidence that the wobbles, shakes and quivers of proteins play a critical role in their ability to function. The findings ...
Molecular & Computational biology
Jul 15, 2022
0
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