Order from disorder in the sarcomere

Alpha-actinin can cross-link actin filaments and anchor them to the Z-disk in sarcomeres. Sarcomeres are a structural unit of myofibril in striated muscle. The FATZ (filamin, α-actinin- and telethonin-binding protein of ...

Protein imaging at the speed of life

To study the swiftness of biology—the protein chemistry behind every life function—scientists need to see molecules changing and interacting in unimaginably rapid time increments—trillionths of a second or shorter.

Eliminating tooth decay: Breakthrough in dental plaque research

Dutch professors Bauke Dijkstra and Lubbert Dijkhuizen have deciphered the structure and functional mechanism of the glucansucrase enzyme that is responsible for dental plaque sticking to teeth. This knowledge will stimulate ...

High speed protein movies to aid drug design

Researchers from the University of Southampton have developed technology to help scientists observe proteins in motion. Understanding how proteins move will allow novel drugs to be designed.

New discovery reveals how the egg controls sperm entry

After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo. This is according to a new study led by researchers ...

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