X-rays pinpoint drug target for Helicobacter pylori

(Phys.org)—Experiments at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have revealed a potential new way to attack common stomach bacteria that cause ulcers and significantly increase the odds ...

Iron-sulfur enzymes as candidates for antibiotic development

The iron-sulfur protein IspH plays a central role in the terpene metabolism of several pathogens. The mechanism of the reaction provides an approach for developing new antibiotics, particularly against malaria and tuberculosis. ...

Intrinsically disordered proteins: A conversation with Rohit Pappu

If you open any biology textbook to the section on proteins, you will learn that a protein is made up of a sequence of amino acids, that the sequence determines how the chain of amino acids folds into a compact structure, ...

A new approach for solving protein structures

(Phys.org)—Using synchrotron x-ray beams to solve the molecular structures of proteins and other large biological molecules has yielded many advances in medicine, such as drug therapies for cancer. Improvements in the techniques ...

SLAC X-ray laser used to probe biomolecules to individual atoms

An international team led by SLAC National Accelerator Laboratory has proved how the world's most powerful X-ray laser can assist in cracking the structures of biomolecules, and in the processes helped to pioneer critical ...

page 9 from 11