It's a chicken and egg question. Where do the infectious protein particles called prions come from? Essentially clumps of misfolded proteins, prions cause neurodegenerative disorders, such as mad cow/Creutzfeld-Jakob disease, ...
Cell & Microbiology
Jul 23, 2011
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Newly synthesized proteins can only fold into their correct three dimensional structure thanks to chaperones. In case of membrane proteins chaperones do not only prevent their aggregation, but also escort them to their destination ...
Cell & Microbiology
Jul 5, 2011
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(Medical Xpress) -- Patricia Clark, the Rev. John Cardinal O’Hara, C.S.C. Associate Professor of Chemistry and Biochemistry at the University of Notre Dame, and Bonnie Berger, professor of applied mathematics at the ...
Biochemistry
Jun 16, 2011
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(PhysOrg.com) -- Researchers outline today a new approach in the potential development of drugs to counter a cellular defect that triggers Parkinson’s and other diseases.
Biochemistry
Jul 14, 2009
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In a paper published in the early online version of Nature Structural and Molecular Biology, researchers at the University of Pittsburgh School of Medicine deconstruct the first steps in an intricate molecular dance that ...
Cell & Microbiology
Mar 8, 2009
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