In-cell engineering can be a powerful tool for synthesizing functional protein crystals with promising catalytic properties, show researchers at Tokyo Tech. Using genetically modified bacteria as an environmentally friendly ...
Bio & Medicine
Jul 25, 2023
0
185
Transcription factor IIH, or TFIIH, pronounced "TF two H," is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the highly regulated enzymatic ...
Cell & Microbiology
Jul 10, 2023
0
92
According to a recently published research paper, an approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes. ...
Biochemistry
Jul 6, 2023
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3
To understand how cells behave, researchers also need to understand the molecules that make them work. "If someone wants to know how the kidney functions, they have to know what's going on inside the kidney cells," says Yang ...
Biotechnology
Mar 16, 2023
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70
Rare-earth elements, also known as lanthanides, are, contrary to what the name suggests, not rare. They are, however, challenging to purify from the environment. Only in the past few years, it became evident that life has ...
Biochemistry
Mar 1, 2023
0
5
CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital have used a next-generation protein degradation technology to study ...
Biotechnology
Jan 25, 2023
0
22
One of the most important classes of human enzymes are protein kinases—signaling molecules that regulate nearly all cellular activities, including growth, cell division, and metabolism. Dysfunction in these cellular pathways ...
Cell & Microbiology
Jan 12, 2023
0
16
The vast majority of vertebrate species living today, including humans, belong to the jawed vertebrate group. The development of articulating jaws during vertebrate evolution was one of the most significant evolutionary transitions ...
Evolution
Nov 25, 2022
0
301
Most cells of humans, animals, plants and fungi contain two sets of chromosomes with specific chromosome numbers—for example, in humans there are two sets of 23 chromosomes as carriers of genetic information. However, polyploid ...
Cell & Microbiology
Nov 9, 2022
0
8
Cyclosporine is one of the most common and effective immunosuppressant drugs used to treat chronic diseases like arthritis and psoriasis, but it comes with a risk of serious side effects. Scientists think that may be because ...
Biochemistry
Sep 27, 2022
0
84
