Mapping signal paths in proteins could reveal new direction for drug development
Using maths previously applied to traffic jams and electrical grids, researchers have developed a new method to map signal propagation in proteins.
Using maths previously applied to traffic jams and electrical grids, researchers have developed a new method to map signal propagation in proteins.
Cell & Microbiology
Aug 26, 2016
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13
G proteins are molecular switches on the insides of cell membranes. They convey important signals to the inner workings of the cells. The associated receptors are targeted by all kinds of medications. Scientists at the Technical ...
Biochemistry
Aug 19, 2016
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0
From growing teeth, bones, and tissue in skin and organs to creating enzymes and hormones, proteins are one of the most diverse and important elements of living organisms. But those varied purposes, along with the interconnectivity ...
Biochemistry
Aug 1, 2016
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600
Whitehead Institute scientists have determined how to use alpaca-derived, single-domain antibody fragments (also called VHHs or nanobodies) to perturb cellular processes in mammalian cells, including the infection of human ...
Cell & Microbiology
Jun 20, 2016
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6
Efficiently releasing stored chemical energy harnessed from renewable sources remains one of the great scientific challenges facing the catalysis research community. Meanwhile, Mother Nature performs this transformation with ...
Materials Science
Jun 3, 2016
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Scientists at the University of North Carolina School of Medicine have developed a way to embed light-responsive switches into proteins so that researchers can use lasers to manipulate protein movement and activity within ...
Biochemistry
Apr 18, 2016
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30
Midlife crisis in the insect world: In a new study, Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have detected age-dependent alterations in metabolism and gene regulation in middle-aged fruitflies, and show ...
Cell & Microbiology
Jan 29, 2016
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15
Lack of adequate sleep can do more than just make you tired. It can short-circuit your system and interfere with a fundamental cellular process that drives physical growth, physiological adaptation and even brain activity, ...
Cell & Microbiology
Oct 30, 2015
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60
An enzyme called telomerase plays a significant role in aging and most cancers, but until recently many aspects of the enzyme's structure could not be clearly seen.
Biochemistry
Oct 15, 2015
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358
Proteins play a large role in sustaining life functions. These molecules ensure that vital reactions, such as DNA replication or metabolism catalysis, are carried out within cells. Protein denaturation is accompanied by the ...
Biochemistry
Oct 1, 2015
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23