Researchers have discovered that three commonly used nonsteroidal anti-inflammatory drugs, or NSAIDs, alter the activity of enzymes within cell membranes. Their finding suggests that, if taken at higher-than-approved doses ...
Cell & Microbiology
Aug 21, 2014
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0
(PhysOrg.com) -- HIV-1 protease inhibitors were added as a component of highly active antiretroviral therapy (HAART) in the mid-1990s, and have played a key role in that treatment regimen ever since. However, the emergence ...
Biochemistry
Sep 17, 2010
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0
(Phys.org)—Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, with collaborators from Harvard University, the University of Madrid, Princeton University, and the University of Zurich, have ...
Biochemistry
Oct 10, 2012
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Understanding how HIV replicates within cells is key for developing new therapies that could help nearly 40 million people living with HIV globally. Now, a team of scientists from the Salk Institute and Rutgers University ...
Molecular & Computational biology
Jul 6, 2022
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77
A study by RIKEN researchers has revealed an important coping mechanism employed by enteric bacteria that allows them to thrive in environments with and without oxygen. The findings could help develop ways to control both ...
Biochemistry
Jan 30, 2015
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20
A RUDN University chemist revised the mechanism of the Henry reaction catalyzed by copper(II) complexes. Thus, using new copper(II) complexes obtained in the same laboratory, he showed that water plays a crucial role in the ...
Analytical Chemistry
Feb 5, 2020
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11
Climate change increases the occurrence of weather extremes. Most focus so far has been on prolonged drought and heat periods. However, the intensity of precipitation forms another threat, as excessive water causes waterlogging ...
Cell & Microbiology
Mar 21, 2023
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7
In new research recently published in the journal Cell Reports, a team of scientists from the University of Massachusetts Amherst delved into the mysteries of how cells weather stress. Using bacterial cells, the researchers ...
Cell & Microbiology
Sep 28, 2022
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38
Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like ...
Bio & Medicine
Dec 12, 2023
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9
In an unexpected new finding, biochemists at the University of Massachusetts Amherst report observing that a damage-containment system in stressed bacteria can become overrun and blocked, but that this leads to cells responding ...
Cell & Microbiology
Aug 6, 2020
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