Many different types of bacteria and viruses can cause pneumonia, but there is no easy way to determine which microbe is causing a particular patient's illness. This uncertainty makes it harder for doctors to choose effective ...
Biochemistry
Jun 13, 2022
0
167
Builders of genetic circuits face the same quandary as builders of digital circuits: testing their designs. Yet unlike bioengineers, engineers have a simple and universal testing tool—the multimeter—that they can touch ...
Molecular & Computational biology
May 21, 2019
0
104
Rice University scientists have designed a tunable virus that works like a safe deposit box. It takes two keys to open it and release its therapeutic cargo.
Bio & Medicine
May 6, 2014
0
0
Gamers have solved the structure of a retrovirus enzyme whose configuration had stumped scientists for more than a decade. The gamers achieved their discovery by playing Foldit, an online game that allows players to collaborate ...
Cell & Microbiology
Sep 18, 2011
3
0
Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like ...
Bio & Medicine
Dec 12, 2023
0
9
Rhomboid proteases are a promising target for new drugs. Now researchers from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) have uncovered a mechanism for regulating enzyme activity. The key role is played ...
Cell & Microbiology
Jul 21, 2023
0
48
During the replication of the SARS-CoV-2 virus, a long string of connected proteins is cleaved apart into individual proteins. This process is interrupted by an FDA-approved drug to treat COVID-19; however, the mechanistic ...
Cell & Microbiology
May 30, 2023
0
49
Climate change increases the occurrence of weather extremes. Most focus so far has been on prolonged drought and heat periods. However, the intensity of precipitation forms another threat, as excessive water causes waterlogging ...
Cell & Microbiology
Mar 21, 2023
0
7
In a paper published Feb. 28 in the journal eLife, a team of researchers headed by Princeton's Alexander Ploss settle a debate about a key protein in hepatitis E (Hep E), which could open the way to developing treatments ...
Molecular & Computational biology
Feb 28, 2023
0
40
Researchers from Department of Microbiology, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has identified novel host protease determinants that facilitate the infection of SARS-CoV-2, ...
Cell & Microbiology
Feb 21, 2023
0
13
