Enzyme helps cancer cells avoid genetic instability

Cancer cells are resourceful survivors with plenty of tricks for staying alive. Researchers have uncovered one of these stratagems, showing how cells lacking the tumor suppressor BRCA1 can resume one form of DNA repair, sparing ...

Anthrax targets

A trawl of the genome of the deadly bacterium Bacillus anthracis has revealed a clutch of targets for new drugs to combat an epidemic of anthrax or a biological weapons attack. The targets are all proteins that are found ...

New molecule has potential to help treat genetic diseases and HIV

(PhysOrg.com) -- Chemists at The University of Texas at Austin have created a molecule that's so good at tangling itself inside the double helix of a DNA sequence that it can stay there for up to 16 days before the DNA liberates ...

Positioning enzymes with ease

Virtually all processes in the human body rely on a unique class of proteins known as enzymes. To study them, scientists want to attach these molecules to surfaces and hold them fast, but this can often be a tricky undertaking.

Proteases inside the cell

(PhysOrg.com) -- A Cardiff-led team has found a unique type of protein inside bacterial cells which could shed new light on organisms such as the disease-causing C. difficile.

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