Much like shoelaces or dangly necklaces, DNA strands can tangle up in unruly knots. Specialized enzymes keep DNA organized when cells divide, so the cells split smoothly and don't get stuck. But in tumor cells, this failsafe ...
Biochemistry
Feb 5, 2019
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8
Genetic studies in mice have identified a molecular mechanism crucial to maintaining egg cells in a dormant state to ensure female fertility. This work by A*STAR identifies a potential method to prevent infertility when the ...
Cell & Microbiology
Apr 5, 2017
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4
University of Tsukuba-led researchers explored the function of the reprogramming factor KLF4 in production of induced pluripotent stem cells (iPSCs). KLF4 was shown to bind upstream of the Tcl1 target gene, which controls ...
Cell & Microbiology
Mar 8, 2017
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31
The importance of a chromatin remodeler gene, Chd1, in regulating the ability of embryonic stem cells to develop into other cell types has been revealed in a new study by A*STAR researchers.
Cell & Microbiology
Aug 26, 2015
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38
Every cell in the body uses phosphorylation, the process of adding a chemical tag to control a protein's function and fate, such as when it moves from one part of a cell to another or binds to other proteins.
Cell & Microbiology
Jun 18, 2015
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9
Researchers in UC's Department of Cancer Biology are collaborating with material scientists from the University of Houston to create and use nanotubes to capture and understand the regulation of proteins involved in a variety ...
Nanomaterials
Jun 11, 2015
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30
Scientists at The Sainsbury Laboratory in Norwich, with collaborators at Michigan State University and the University of Illinois, have unveiled a new way in which plants perceive pathogens to activate immunity.
Biotechnology
Mar 13, 2014
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0
For the past several years, Min Guo, an assistant professor at The Scripps Research Institute, has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process ...
Cell & Microbiology
Nov 15, 2012
4
0
(Phys.org) -- How better to find out what effect ionizing radiation has on human skin than by using the real thing? Researchers at Pacific Northwest National Laboratory did that by performing a quantitative mass spectrometry ...
Biochemistry
Apr 24, 2012
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0
A Purdue University scientist's nanopolymer would make it easier and cheaper for drug developers to test the effectiveness of a widely used class of cancer inhibitors.
Analytical Chemistry
Mar 16, 2011
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