Related topics: drug · protein · cancer · cells · cancer cells

Experimental evolution reveals how bacteria gain drug resistance

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in experimentally evolving the common bacteria Escherichia coli under pressure from a large number of individual antibiotics. ...

Computer vision helps find binding sites in drug targets

Scientists from the iMolecule group at Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE) developed BiteNet, a machine learning (ML) algorithm that helps find drug binding sites, i.e. potential ...

Antibacterial prodrug by targeting intracellular metabolite

National University of Singapore researchers have developed an approach to selectively target pathogenic bacteria by harnessing an intracellular metabolite known as formate, abundant in these bacteria, as a new antimicrobial ...

New method for combating antibiotic resistance in microbes

Bacteria in biofilms are 1,000 times more resistant to antibiotics, disinfectants, mechanical treatment, and other types of stress. A chemist from RUDN University suggested a method to prevent the formation of biofilms and ...

Researchers use waveguides for sensitive protease monitoring

For the first time, researchers have detected protease activity with surface-enhanced Raman spectroscopy (SERS) performed using a tiny waveguide. The work paves the way to real-time, label-free lab-on-a-chip protease monitoring, ...

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