Human Argonaute proteins: To slice or not to slice?
What makes one Argonaute a slicer and another one not? Human Argonaute proteins are key players in the gene regulation process known as RNA interference, RNAi. Professor Joshua-Tor's group of Cold Spring Harbor Laboratory ...
That four-leaf clover you found may not be a four-leaf clover
(Phys.org) —Are four-leaf clovers becoming more common? That was the question put to me by a reader recently. Apparently her kids are finding four-leaf clovers on a daily basis as they walk home from school. ...
DNA gridlock: Cells undo glitches to prevent mutations
Roughly six feet of DNA are packed into every human cell, so it is not surprising that our genetic material occasionally folds into odd shapes such as hairpins, crosses and clover leafs. But these structures ...
Team finds key to gene-silencing activity, opens door to new class of therapies
A team led by scientists at The Scripps Research Institute (TSRI) has found how to boost or inhibit a gene-silencing mechanism that normally serves as a major controller of cells' activities. The discovery ...
Scientists revolutionize the creation of genetically altered mice to model human disease
Whitehead Institute Founding Member Rudolf Jaenisch, who helped transform the study of genetics by creating the first transgenic mouse in 1974, is again revolutionizing how genetically altered animal models are created and ...
Pig stress syndrome linked to gene defect
The tulip tree reveals mitochondrial genome of ancestral flowering plant
The extraordinary level of conservation of the tulip tree (Liriodendron tulipifera) mitochondrial genome has redefined our interpretation of evolution of the angiosperms (flowering plants), finds research in bio ...
How herpesvirus invades nervous system: Viral protein hijacks cellular machinery and grabs the wheel
Northwestern Medicine scientists have identified a component of the herpesvirus that "hijacks" machinery inside human cells, allowing the virus to rapidly and successfully invade the nervous system upon initial exposure.
Out of Africa date brought forward
(Phys.org) —A study on human mitochondrial DNA has led to a new estimate of the time at which humans first began to migrate out of Africa, which was much later than previously thought.
Team develops psoriasis drug
Ben-Gurion University of the Negev (BGU) researchers, in collaboration with Teva Pharmaceutical Industries Ltd., have developed a promising drug candidate to treat psoriasis. The finding was reported in a new paper published ...
Skulls of early humans carry telltale signs of inbreeding, study says
Buried for 100,000 years at Xujiayao in the Nihewan Basin of northern China, the recovered skull pieces of an early human exhibit a now-rare congenital deformation that indicates inbreeding might well have ...
Blind flies without recycling: How Drosophila recovers the neurotransmitter histamine
Long-term evolution is 'surprisingly predictable,' experiment shows