Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value. One of these hidden gems is (–)-jerantinine A (JA), a molecule with remarkable anticancer properties, ...
Biochemistry
Mar 23, 2023
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26
A team of chemists at MIT has found that using peptides instead of DNA fragments to tag small molecules can speed up the drug discovery process. Their research is published in the journal Science.
Cell membranes are barriers that maintain cellular homeostasis, and the intracellular delivery of biologically functional molecules, including peptides, proteins, and nucleic acids to manipulate cellular functions. Conventional ...
Bio & Medicine
Mar 6, 2023
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62
In a recent study, researchers from the Department of Organic Chemistry (OC) and Materials Research Centre (MRC), Indian Institute of Science (IISc), show that surface modifications of two-dimensional molybdenum disulfide ...
Bio & Medicine
Mar 2, 2023
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43
Scientists at St. Jude Children's Research Hospital have demonstrated how drug makers can avoid two key problems: toxicity and resistance. The researchers made slight changes to a small molecule to reduce its metabolism and ...
Biochemistry
Feb 28, 2023
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73
Researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of Spanish National Research Council (CSIC) have developed a series of photosensitive molecule drugs that can be reversibly activated by external light, ...
Biochemistry
Feb 16, 2023
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60
Hokkaido University researchers have developed a novel method to design and develop peptide antibiotics in large numbers, which will prove critical to controlling antibiotic resistance.
Biochemistry
Feb 8, 2023
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65
Two catalysts working in tandem enable inexpensive formate salts to perform difficult dearomative reactions, resulting in products potentially useful for drug development.
Materials Science
Feb 7, 2023
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19
Pharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production. Now, in a study recently published in Science, researchers ...
Analytical Chemistry
Feb 2, 2023
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123
A team of researchers at the University of Queensland has discovered some of the mechanisms involved when bacteria become more resistant to antibacterial drugs after exposure to antidepressant drugs. In their paper published ...
