A general chemical principle for creating closure-stabilizing integrin inhibitors
Name a biological function, and proteins called integrins are probably involved in it.
Name a biological function, and proteins called integrins are probably involved in it.
Biochemistry
Sep 16, 2022
0
35
Drug molecules and biofuels can be made to order by living cell factories, where biological enzymes do the job. Now, researchers at Chalmers University of Technology have developed a computer model that can predict how fast ...
Biochemistry
Aug 31, 2022
0
452
A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type ...
Biochemistry
Aug 10, 2022
0
59
Urinary tract infections are common, yet are increasingly tough to treat because the bacteria that cause them are becoming resistant to many antibiotics. Now, in ACS Central Science, researchers report a new molecule that ...
Molecular & Computational biology
Aug 10, 2022
1
187
Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic aza-arenes, which are commonly ...
Biochemistry
Aug 9, 2022
0
313
A new technique that can analyze how drug molecules bind to proteins in tissue samples could offer an improved route to drug discovery and development.
Biochemistry
Jul 14, 2022
0
18
Using a new method, scientists are better able to distinguish between mirror-image substances. This is important amongst others in drug development, because the two variants can cause completely different effects in the human ...
Optics & Photonics
Jul 5, 2022
0
23
Researchers at Karolinska Institutet and SciLifeLab in Sweden describe in a study published in Science how they have improved the ability of a protein to repair oxidative DNA damage and created a new protein function. Their ...
Biochemistry
Jun 23, 2022
0
61
We live in a world made and run by RNA, the equally important sibling of the genetic molecule DNA. In fact, evolutionary biologists hypothesize that RNA existed and self-replicated even before the appearance of DNA and the ...
Bio & Medicine
May 2, 2022
0
1882
Scientists at Scripps Research have invented a way to image, across different tissues and with higher precision than ever before, where drugs bind to their targets in the body. The new method could become a routine tool in ...
Cell & Microbiology
Apr 29, 2022
0
102