'Nanobodies' could hold clues to new COVID-19 therapies

WEHI researchers are studying 'nanobodies' – tiny immune proteins made by alpacas—in a bid to understand whether they might be effective in blocking SARS-CoV-2, the virus that causes COVID-19.

Researchers elucidate the mechanics of cellular attachment

For cells to assemble into tissues and whole organs, the extracellular matrix (ECM) as well as integrins are required. The ECM forms a kind of extra-cellular protein meshwork; the integrins are surface proteins, which cells ...

A step toward a universal flu vaccine

Each year, the flu vaccine has to be redesigned to account for mutations that the virus accumulates, and even then, the vaccine is often not fully protective for everyone.

New mechanism for anti-infection effects of dietary fiber

New research in mice has uncovered a previously unknown interaction between molecules derived from dietary fiber and an immune cell protein, which triggers protection against infection with Salmonella bacteria. Hitoshi Tsugawa ...

Human white blood cells use molecular paddles to swim

Human white blood cells, known as leukocytes, swim using a newly described mechanism called molecular paddling, researchers report in the September 15th issue of Biophysical Journal. This microswimming mechanism could explain ...

How plants shut the door on infection

Plants have a unique ability to safeguard themselves against pathogens by closing their pores—but until now, no one knew quite how they did it. Scientists have known that a flood of calcium into the cells surrounding the ...

Cryo-EM study yields new clues to chicken pox infection

Despite decades of study, exactly how herpesviruses invade our cells remains something of a mystery. Now researchers studying one herpesvirus, the varicella zoster virus (VZV) that causes chicken pox, may have found an important ...

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