When editing bacteria with CRISPR, less is more

Systematically attenuating DNA targeting activity can achieve CRISPR-driven editing in bacteria, greatly boosting colony counts and even increasing the frequency of precise genome editing. This was shown in a study of the ...

For plant geneticists, some genes are double the trouble

When plant geneticists find a gene that improves crop yields, they want to try to insert that same change into other crops. But Cold Spring Harbor Laboratory Professor and HHMI Investigator Zachary Lippman cautions that ...

Researchers pioneer new method to edit genes in human cells

Over the past decade, the CRISPR genome-editing system has revolutionized molecular biology, giving scientists the ability to alter genes inside living cells for research or medical applications. Now, researchers at Gladstone ...

CRISPRing the microbiome is just around the corner

To date, CRISPR enzymes have been used to edit the genomes of one type of cell at a time: They cut, delete or add genes to a specific kind of cell within a tissue or organ, for example, or to one kind of microbe growing in ...

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