Two teams working independently of one another have identified several CRISPR-Cas12a inhibitors. The first team was made up of members from the University of California, Berkeley, the other had members from Massachusetts ...
Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have engineered changes to the revolutionary CRISPR-Cas9 genome editing system that significantly cut down on "off-target" ...
Biotechnology
Dec 1, 2015
0
138
Human embryos start as a tiny mass of cells that are all the same. The first step in growing from a homogenous ball of cells into a complex individual with distinct organs and tissues is for the cells to divide into distinct ...
Cell & Microbiology
Oct 9, 2018
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253
Greater resistance to pests, less sensitivity to drought, higher yields – this is just a small selection of the requirements that crops will have to fulfil in future. Humanity needs new crops that can withstand the changes ...
Biotechnology
Apr 14, 2016
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461
By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically—an approach that could help identify novel targets for therapies against ...
Cell & Microbiology
Apr 3, 2015
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817
Genome editing technologies have revolutionized biomedical science, providing a fast and easy way to modify genes. However, the technique allowing scientists to carryout the most precise edits, doesn't work in cells that ...
Biotechnology
Oct 19, 2017
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267
A new technology called CRISPR is making international headlines as a monumental leap in genetic engineering. CRISPR, an acronym for "clustered regularly interspaced short palindromic repeats," is a genome-editing technology ...
Biotechnology
Jan 27, 2017
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22
CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows ...
Biotechnology
Aug 9, 2022
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3005
In an era of widespread genetic sequencing, the ability to edit and alter an organism's DNA is a powerful way to explore the information within and how it guides biological function.
Biotechnology
Aug 23, 2013
1
0
Although the genome editing system known as CRISPR/Cas has revolutionized genetic research in cell lines, its overall efficiency has been relatively poor when used to generate genetically altered animals for disease modeling. ...
Biotechnology
Mar 24, 2015
0
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