As CRISPR-Cas9 starts to move into clinical trials, a new study published in Nature Methods has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.
Biotechnology
May 29, 2017
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14197
A team including the scientist who first harnessed the revolutionary CRISPR-Cas9 system for mammalian genome editing has now identified a different CRISPR system with the potential for even simpler and more precise genome ...
Biotechnology
Sep 25, 2015
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Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.
Biotechnology
Jul 11, 2018
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526
Chinese genetic scientists must not be put off sensitive research by ethical concerns, the team behind a controversial study on modified human embryos said Wednesday as debate erupted over the paper.
Biotechnology
Apr 13, 2016
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263
Sugarcane is one of the most productive plants on Earth, providing 80 percent of the sugar and 30 percent of the bioethanol produced worldwide. Its size and efficient use of water and light give it tremendous potential for ...
Biotechnology
Jul 12, 2021
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991
As a new tool in CRISPR genome editing, Cpf1 has sparked an explosion of interest for its attributes that differ from Cas9: It requires only a single RNA that CRISPR RNA assembly is simpler; its staggered cleavage patterns ...
Biotechnology
Jun 6, 2016
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136
Don't expect designer babies any time soon—but a major new ethics report leaves open the possibility of one day altering human heredity to fight genetic diseases, with stringent oversight, using new tools that precisely ...
Biotechnology
Feb 14, 2017
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1046
Scientists at the Wellcome Sanger Institute have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies ...
Biotechnology
Jul 16, 2018
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107
CRISPR/Cas9 is a new method for targeted genetic changes. Together with other methods, it is part of the so-called genome editing toolbox. At the moment, genome-editing is mostly discussed in the context of medical applications, ...
Biotechnology
Feb 15, 2016
0
830
The genome editing system CRISPR has become a hugely important tool in medical research, and could ultimately have a significant impact in fields such as agriculture, bioenergy, and food security.
Biotechnology
Oct 24, 2018
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392
