Related topics: gene expression

Toward new drugs that turn genes on and off

Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, cancer and a ...

Researchers reveal largest catalog of gene activators

University of Toronto researchers have created a first-in-class functional catalog of proteins that activate gene expression, with implications for tailored therapy for cancer and other diseases that occur when wrong genes ...

Proteins barge in to turn off unneeded genes

(Phys.org)—The sorcerer's apprentice started a water-carrying system, but couldn't stop it, and soon he was up to his neck in water, and trouble. Living cells have a better design: When they activate a gene, they have a ...

Rethinking reprogramming: A new way to make stem cells

A paper published by Cell Press in the April 8th issue of the journal Cell Stem Cell reveals a new and more efficient method for reprogramming adult mouse and human cells into an embryonic stem cell-like state and could lead ...

Three-in-one approach boosts the silencing power of CRISPR

Originally discovered as a bacterial mode of defense against invading viruses, the remarkable ability of CRISPR-Cas9 to modify specific locations of DNA has made it a researcher favorite among gene editing tools. The ongoing ...

New genes on "deteriorating" Y chromosome

The Y chromosome, which is found only in males, is difficult to decode even with the latest sequencing technologies. Among evolutionary biologists, the question as to which genes lie on the male sex chromosome and where they ...

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