In a tiny worm, a close-up view of where genes are working

Scientists have long prized the roundworm Caenorhabditis elegans as a model for studying the biology of multicellular organisms. The millimeter-long worms are easy to grow in the lab and manipulate genetically, and have only ...

Single-cell RNA profiling

An LMU team has improved both the sensitivity and efficiency of a popular method for single-cell RNA sequencing, which yields a molecular fingerprint for individual cells based on their patterns of gene activity.

Programming synthetic molecular codes to turn genes 'on'

A team of researchers in Japan developed a synthetic molecular code to script gene activation. The process, described in the Journal of the American Chemical Society, could lead to future gene-based therapies for a wide array ...

Does physical activity influence the health of future offspring?

Physical and mental exercise can affect the learning ability of future offspring, at least in mice. This particular form of inheritance is mediated by certain RNA molecules that influence gene activity. These molecules accumulate ...

Researchers measure gene activity in single cells

For biologists, a single cell is a world of its own: It can form a harmonious part of a tissue, or go rogue and take on a diseased state, like cancer. But biologists have long struggled to identify and track the many different ...

Active genetics technology opens new horizons

In 2015, University of California San Diego biologists Ethan Bier and Valentino Gantz developed a breakthrough technology known as "active genetics," which results in parents transmitting a genetic trait to most of their ...

More genes are active in high-performance maize

When two maize inbred lines are crossed with each other, an interesting effect occurs: The hybrid offspring have a significantly higher yield than either of the two parent plants. Scientists at the University of Bonn have ...

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