Supercomputer simulations by RIKEN researchers have revealed how drug binding to a protein target changes as the surrounding environment becomes more cluttered with other proteins. These simulations could help improve drug ...
Biotechnology
Oct 21, 2021
0
73
A team of researchers at the University of Massachusetts Amherst has announced a major new advance in understanding how our genetic information eventually translates into functional proteins—one of the building blocks of ...
Molecular & Computational biology
Oct 12, 2021
0
120
In recent years, scientists have created music based on the structure of proteins as a creative way to better popularize science to the general public, but the resulting songs haven't always been pleasant to the ear. In a ...
Other
Sep 29, 2021
0
44
Researchers use synthesized small molecule tools, known as chemical probes, with druglike properties to identify specific types of proteins in order to find potential new drug leads. However, currently-available technologies ...
Biochemistry
Sep 9, 2021
0
82
Researchers have identified two sugar-binding proteins that impede the viral entry of circulating SARS-CoV-2 variants. The team, spearheaded by researchers at IMBA—Institute of Molecular Biotechnology of the Austrian Academy ...
Cell & Microbiology
Aug 10, 2021
1
6650
Thousands of proteins undergo arginine N-methylation, a widespread post-translational modification catalyzed by several protein arginine methyltransferases (PRMTs) that covalently link methyl groups to arginine side chains. ...
Biotechnology
Jul 19, 2021
0
6
Scientists have organized proteins—nature's most versatile building blocks—in desired 2D and 3D ordered arrays while maintaining their structural stability and biological activity. They built these designer functional ...
Biotechnology
Jun 25, 2021
0
16
The SARS-CoV-2 papain-like protease (PLpro) plays an essential role in processing viral proteins needed for replication. In addition, the enzyme can cut and inactivate some human proteins important for an immune response. ...
Cell & Microbiology
Jun 9, 2021
0
6
Proteins are the workhorses of cells, responsible for almost all biological functions that make life possible.
Molecular & Computational biology
May 6, 2021
0
4
In the cell nucleus, histones play a crucial role packaging DNA into chromatin. Histones are however very sticky to both DNA and RNA, so to ensure they are transported to the cell nucleus after synthesis and bind to the right ...
Cell & Microbiology
Apr 14, 2021
0
18
