An unprecedented molecular view of the critical early events in gene expression, a process essential for all life, has been provided by researchers at Georgia State University, the University of California at Berkeley and ...
Biotechnology
May 11, 2016
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861
(Phys.org) —In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of bacterial metabolism. ...
Biochemistry
Apr 9, 2013
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An team of Rutgers University scientists led by Richard H. Ebright and Eddy Arnold has determined the three-dimensional structure of the transcription initiation complex, the key intermediate in the process by which cells ...
Cell & Microbiology
Oct 18, 2012
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Indiana University biologists have found that specific types of RNA polymerase enzymes, the molecular machines that convert DNA into RNA, can differ in function based on variation in the parts -- in this case protein subunits ...
Biotechnology
Mar 1, 2012
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(Phys.org) -- When genetic information is read from the genetic blueprint DNA, RNA polymerase II translates it into RNA molecules. The C-terminal domain, abbreviated as CTD, is an important area of the polymerase molecule. ...
Biotechnology
May 21, 2012
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A research collaboration that combines novel "big-data" informatics tools with expertise in basic biology has uncovered details of an essential process in life: how a crucial enzyme locates the site on DNA where it begins ...
Cell & Microbiology
Mar 3, 2016
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15
Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...
Cell & Microbiology
Feb 23, 2011
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Researchers have provided new insight on the mechanism underlying the control of gene expression in all living organisms, according to a study published today in eLife.
Cell & Microbiology
Jan 8, 2019
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100
For 10 years, Patrick Cramer and his colleagues at Ludwig-Maximilians-Universitaet (LMU) in Munich have probed the structure of RNA polymerase I, a crucial cog in the machinery of all cells. Now they unveil the full three-dimensional ...
Cell & Microbiology
Oct 24, 2013
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0
Scientists have discovered how a common virus in the human gut infects and takes over bacterial cells—a finding that could be used to control the composition of the gut microbiome, which is important for human health.
Biotechnology
Nov 18, 2020
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