Current arthritis medications can ease the pain, but stopping the progression of the disease requires more aggressive treatments: use of very limited available drugs or surgical intervention. University of Missouri researchers ...
Feb 18, 2009
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Johns Hopkins scientists have discovered a new mode of action for enzymes immersed in cellular membranes. Their experiments suggest that instead of recognizing and clipping proteins based on sequences of amino acids, these ...
Cell & Microbiology
Nov 16, 2012
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Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...
Cell & Microbiology
Feb 23, 2011
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The structure of the critical quality control checkpoint enzyme that oversees the production of thousands of secreted glycoproteins has been solved by a fruitful collaborative effort at Diamond Light Source. The study, recently ...
Biochemistry
Jul 25, 2017
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Scientists are reporting development of the first practical way to make large amounts of a promising new anti-cancer substance that kills cancer cells differently than existing medicines. Their article on synthesis of the ...
Biochemistry
Jan 16, 2013
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A new study reveals that several drugs for treating haematological cancers are less effective than expected in inhibiting a special enzyme. Researchers have also identified new lead compounds that could potentially improve ...
Biochemistry
Jul 26, 2018
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Scientists studying plant cell walls—structural supports that help plants overcome the downward pull of gravity—have discovered mechanistic details of a protein involved in the assembly of lignin, a key cell-wall component. ...
Biotechnology
Apr 8, 2019
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72
The cell signaling pathway known as Wnt, commonly activated in cancers, causes internal membranes within a healthy cell to imprison an enzyme that is vital in degrading proteins, preventing the enzyme from doing its job and ...
Cell & Microbiology
Dec 23, 2010
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An enzyme is a tiny, well-oiled machine. A class of proteins that are made up of multiple, interlocking molecular components, enzymes perform a variety of tasks inside each cell. However, precisely how these components work ...
Cell & Microbiology
Aug 8, 2013
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(PhysOrg.com) -- Zemer Gitai, an assistant professor of molecular biology at Princeton University, members of his laboratory, and scientists from the California Institute of Technology have published results in Nature Cell ...
Cell & Microbiology
Aug 2, 2010
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