Cryogenic (frozen) protein structures are central to understanding function and developing drugs. Scientists at St. Jude Children's Research Hospital have created an algorithm to reveal when freezing the proteins may create ...
Biochemistry
Jun 7, 2022
0
72
FMI researchers have identified a synthetic protein that dampens the activity of a cellular pathway involved in viral infection. The findings could help to develop drugs that combat viruses such as influenza A and Zika.
Cell & Microbiology
May 11, 2022
0
117
Scientists rely increasingly on models trained with machine learning to provide solutions to complex problems. But how do we know the solutions are trustworthy when the complex algorithms the models use are not easily interrogated ...
Analytical Chemistry
May 2, 2022
0
95
Researchers at Stockholm University have applied advanced electron microscopy techniques to finally unveil the structure of the widely used and century-old active pharmaceutical ingredient bismuth subsalicylate. The discovery ...
Analytical Chemistry
Apr 13, 2022
0
31
Scientists at Scripps Research and the National Institute of Dental and Craniofacial Research have discovered a special type of cell that resides in salivary glands and is likely crucial for oral health.
Cell & Microbiology
Apr 12, 2022
0
54
Scientists have developed a new technique to accelerate the discovery of cancer-fighting drugs. The technique identifies molecules that can shut down dangerous proteins before they wreak disease-triggering havoc, by blocking ...
Biochemistry
Apr 7, 2022
0
85
In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled ...
Cell & Microbiology
Apr 7, 2022
0
48
The number of potential therapeutic targets on the surfaces of human proteins is much greater than previously thought, according to the findings of a new study in the journal Nature.
Molecular & Computational biology
Apr 6, 2022
1
216
A research team led by Prof. Dai Wen from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS), in collaboration with Associate Prof. Zhang Zehui from South-Central University for Nationalities, ...
Materials Science
Mar 31, 2022
0
94
Soft and immobile, sea sponges may appear inert, but these simple animals are rich with chemistry. From them, scientists have uncovered plenty of biologically active compounds, some of which have gone on to become medications. ...
Biochemistry
Mar 20, 2022
1
284
