Soft and immobile, sea sponges may appear inert, but these simple animals are rich with chemistry. From them, scientists have uncovered plenty of biologically active compounds, some of which have gone on to become medications. ...
Biochemistry
Mar 20, 2022
1
284
A potential cornucopia of neuroactive compounds, which might yield clues to the design of future psychiatric and neurological drugs, has become more accessible to synthetic chemists, thanks to new work from Scripps Research.
Biochemistry
Mar 17, 2022
0
81
The amount of structural data on protein drug targets continues to grow. However, successfully mining this data to form testable hypotheses that drive drug discovery can prove challenging. Selectivity for the target protein ...
Biochemistry
Mar 2, 2022
0
11
A key technical challenge in creating new sulfur-based medicines has been overcome by scientists at Nanyang Technological University, Singapore (NTU Singapore), leading to the prospect of many new therapeutic 'weapons' in ...
Biochemistry
Feb 14, 2022
0
42
Pharmaceutical researchers speak of a hit when they come across a promising substance with a desired effect in early drug discovery. Unfortunately, hits are rarely bull's-eyes, often showing undesirable side effects that ...
Biochemistry
Jan 27, 2022
0
92
A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis—the process of cell death that is usually caused by infections and results in excess inflammation in ...
Cell & Microbiology
Jan 10, 2022
0
512
A study by researchers affiliated with institutions in Brazil, Germany and Finland proposes a new standard for computer simulation that promises to accelerate the search for novel bioactive compounds against the virus that ...
Molecular & Computational biology
Dec 8, 2021
0
12
Medicines come from chemical reactions, and better chemical reactions lead to better medicines.
Biochemistry
Oct 29, 2021
3
81
Just north of Antarctica and a little east of the southern tip of South America is the Scotia Sea. Besides glimpses of an occasional iceberg, these waters offer little to tourists.
Materials Science
Oct 19, 2021
0
14
Deep learning has radically changed the field of artificial intelligence. Now neural networks are revolutionizing the way that we discover new drugs. We talk to Francesca Grisoni, assistant professor at the department of ...
Biotechnology
Sep 16, 2021
0
240
