Human MutT homolog 1 (hMTH1) protein acts as the primary enzyme for breaking down (hydrolyzing) damaged (oxidized) deoxynucleoside triphosphates (dNTPs) the substrates of DNA synthesis. Recently, hMTH1 has drawn attention ...
Biochemistry
Mar 29, 2017
0
5
Synthetic DNA allows scientists to expand the breadth and depth of their genomic research. In this study researchers from the U.S. Department of Energy Joint Genome Institute (DOE JGI) have developed a suite of build-optimization ...
Biotechnology
Mar 15, 2017
0
6
Humanity may soon generate more data than hard drives or magnetic tape can handle, a problem that has scientists turning to nature's age-old solution for information-storage—DNA.
Biotechnology
Mar 2, 2017
10
10738
Despite the vast diversity of organisms on the planet that express enzymes for the conversion of carbon dioxide into such organic compounds as sugars - as plants do through photosynthesis - the efforts to harness these capabilities ...
Biotechnology
Nov 17, 2016
0
174
A research team led by scientists at the Icahn School of Medicine at Mount Sinai (ISMMS) has solved the three-dimensional structure of a key protein that helps damaged cellular DNA repair itself. Investigators say that knowing ...
Cell & Microbiology
Oct 25, 2016
1
44
Cisplatin is one of the most widely used agents in cancer chemotherapy. Its mode of action is cross-linking of the DNA, which can kill cells. But which part of the genome is more affected, and which is less affected? A Chinese ...
Biochemistry
Oct 21, 2016
0
59
Eukaryotic cells, including human cells, form paired condensed chromosomes before cell division. The paired chromosomes are then equally divided into daughter cells. Prokaryotic cells, including bacteria, do not have such ...
Cell & Microbiology
Oct 21, 2016
0
9
Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus, promoting intact DNA ...
Cell & Microbiology
Sep 12, 2016
0
7
Aging, neurodegenerative disorders and metabolic disease are all linked to mitochondria, structures within our cells that generate chemical energy and maintain their own DNA. In a fundamental discovery with far-reaching implications, ...
Cell & Microbiology
Jul 15, 2016
1
50
Newcastle University scientists have discovered a new essential sequence within bacterial genomes required for DNA replication - the second ever to be discovered and the first for 30 years.
Cell & Microbiology
Jun 8, 2016
0
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