Cell division is fundamental for life, allowing organisms to grow, repair tissues, and reproduce. For a cell to divide, all the DNA inside the cell (the genome) must first be copied, in a process called DNA replication. But ...
Cell & Microbiology
Sep 29, 2022
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8
DNA replication and repair happens thousands of times a day in the human body and most of the time, people don't notice when things go wrong thanks to the work of Replication protein A (RPA), the "guardian of the genome." ...
Molecular & Computational biology
Aug 10, 2022
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14
Knowing the structure of a complex biological system isn't nearly enough to understand how it works. It helps to know how the system moves.
Biotechnology
Aug 9, 2022
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130
In humans, a fertilized egg is no guarantee of reproductive success. Most embryos stop developing and perish within days of fertilization, usually because they have an abnormal number of chromosomes. Now, researchers at Columbia ...
Cell & Microbiology
Jul 19, 2022
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47
An article published in the journal Frontiers in Cellular and Infection Microbiology reports a study by researchers at the State University of Campinas (UNICAMP) and the University of São Paulo (USP) in Brazil showing how ...
Cell & Microbiology
Jul 18, 2022
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33
Researchers at the Francis Crick Institute have uncovered how the double helix structure of DNA is opened to allow DNA replication. The work could lead to further studies to better understand this process including how it ...
Molecular & Computational biology
Jun 16, 2022
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15
When cells reproduce, the internal mechanisms that copy DNA get it right nearly every time. Rice University bioscientists have uncovered a tiny detail that helps understand how the process could go wrong.
Cell & Microbiology
May 9, 2022
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368
Healthy human cells have two (diploid) sets of chromosomes. However, it may also happens that cells have a tetraploid (quadruple) set. Usually, they do not divide further and die, but some cells can escape this fate. An international ...
Cell & Microbiology
Apr 8, 2022
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63
DNA is often likened to a blueprint. The particular sequence of As, Cs, Gs, and Ts in DNA provides information for building an organism.
Molecular & Computational biology
Mar 21, 2022
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73
When something goes wrong during DNA replication, cells call their own version of 911 to pause the process and fix the problem—a failsafe that is critical to maintaining health and staving off disease.
Cell & Microbiology
Mar 21, 2022
0
35
