If you've ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape?
Cell & Microbiology
Aug 30, 2018
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4
Researchers from the University of Illinois at Chicago are the first to describe why CRISPR gene editing sometimes fails to work, and how the process can be made to be much more efficient.
Biotechnology
Jul 11, 2018
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526
Cells propagate by making copies of themselves via genome replication. Arguably, replication of DNA is the most fundamental and conserved mechanism of all life forms. Cracking the secret of how this process is achieved with ...
Biochemistry
Jul 6, 2018
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The shape of DNA can be changed with a range of triggers including copper and oxygen—according to new research from the University of East Anglia.
Biochemistry
May 24, 2018
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It's been 65 years since the paper "Molecular structure of nucleic acids," by James Watson and Francis Crick, was published in Nature. Or, more prosaically, the paper that first describes the structure of DNA as we know it ...
Biotechnology
Apr 26, 2018
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9
It's DNA, but not as we know it. In a world first, Australian researchers have identified a new DNA structure—called the i-motif—inside cells. A twisted 'knot' of DNA, the i-motif has never before been directly seen inside ...
Biochemistry
Apr 23, 2018
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267
Not only can synthetic molecules mimic the structures of their biological models, they can also take on their functions and may even successfully compete with them, as an artificial DNA sequence designed by Ludwig-Maximilians-Universitaet ...
Biochemistry
Apr 2, 2018
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59
It may be the most famous structure in biology, but it wasn't until a few years ago that biophysicist Enzo di Fabrizio and his colleagues took the first direct images of the DNA double helix with an electron microscope.
Materials Science
Mar 14, 2018
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5
If you had to copy billions of letters from one sheet of paper to another, you'd probably make a few mistakes. So it might not come as a surprise that when DNA makes a copy of its three-billion-base genetic code, it can slip ...
Cell & Microbiology
Jan 31, 2018
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506
Life would be impossible if the DNA in dividing cells were replicated with anything less than near-perfect precision. Every time a nucleated cell commits to becoming two cells, every "letter" of its genome must be replicated ...
Cell & Microbiology
Oct 23, 2017
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