Drugs can only work if they stick to their target proteins in the body. Assessing that stickiness is a key hurdle in the drug discovery and screening process. New research combining chemistry and machine learning could lower ...
Biotechnology
Mar 15, 2021
0
362
The online cover story of Science Advances this week features a conceptual gastrointestinal (GI) microdevice, developed by a research team for extended drug release. Drug delivery platforms for extended drug release have ...
Philosopher Nicholas Rescher once wrote, "Scientific discoveries are often made not on the basis of some well-contrived plan of investigation, but through some stroke of sheer luck."
Astronomy
Apr 21, 2020
1
771
A new study from the lab of Thomas Mallouk shows how microscale "rockets," powered by acoustic waves and an onboard bubble motor, can be driven through 3-D landscapes of cells and particles using magnets. The research was ...
Bio & Medicine
Oct 28, 2019
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190
Researchers have used artificial intelligence to make new discoveries, and confirm old ones, about one of nature's best-known mimics, opening up whole new directions of research in evolutionary biology.
Evolution
Aug 14, 2019
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489
Researchers have designed a machine learning algorithm for drug discovery which has been shown to be twice as efficient as the industry standard, which could accelerate the process of developing new treatments for disease.
Biochemistry
Feb 11, 2019
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160
Researchers have launched an ultra-large virtual docking library expected to grow to more than 1 billion molecules by next year. It will expand by 1000-fold the number of such "make-on-demand" compounds readily available ...
Biochemistry
Feb 6, 2019
0
59
Scientists have revealed the structure of a virus infecting bacteria that thrive in 160-degree hot springs in places like Yellowstone National Park in Wyoming.
Cell & Microbiology
Feb 4, 2019
0
130
Most malaria drugs are designed to reduce symptoms after infection. They work by blocking replication of the disease-causing parasites in human blood, but they don't prevent infection or transmission via mosquitoes. What's ...
Cell & Microbiology
Dec 6, 2018
0
64
Regulation of gene expression—turning genes on or off, increasing or decreasing their expression—is critical for defining cell identity during development and coordinating cellular activity throughout the cell's lifetime. ...
Cell & Microbiology
Nov 19, 2018
0
70
