Many important medicines, such as antibiotics and anticancer drugs, are derived from natural products of bacteria. The enzyme complexes that produce these active ingredients have a modular design that makes them ideal tools ...
Cell & Microbiology
Mar 21, 2024
0
51
Designed to meet the urgent need for insights into the molecular intricacies of SARS-CoV-2 infection, BioExcel-CV19 is a repository for molecular dynamics (MD) simulations.
Molecular & Computational biology
Jan 8, 2024
0
49
The Chirik Group at the Princeton Department of Chemistry is chipping away at one of the great challenges of metal-catalyzed C–H functionalization with a new method that uses a cobalt catalyst to differentiate between bonds ...
Analytical Chemistry
Dec 7, 2023
0
14
Researchers report in the journal Nature that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that—once it infects a person—is notoriously ...
Cell & Microbiology
Nov 22, 2023
0
15
Researchers from the University of B.C. and the BC Provincial Toxicology Center (BCPTC) have developed a more efficient way to find out which new 'designer drugs' are circulating in the community.
Analytical Chemistry
Nov 15, 2023
0
28
For diabetes patients who must give themselves frequent insulin injections, the risk of low blood sugar can be life-threatening. A potential solution is a type of engineered insulin that circulates in the body and springs ...
Biochemistry
Sep 20, 2023
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1
The crystal structure of a human endogenous reverse transcriptase has similarities to HIV reverse transcriptase, a well-known tractable drug target, which will help design drugs to treat cancer and other diseases, according ...
Biochemistry
Jun 30, 2022
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43
Every time a new cancer drug is announced, it represents hundreds of researchers spending years behind the scenes working to design and test a new molecule. The drug has to be not only effective, but also as safe as possible ...
Biochemistry
Apr 29, 2022
0
104
A little wiggle room might be just what the doctor ordered.
Biochemistry
Dec 22, 2021
0
52
Scientists at EMBL Hamburg and CSSB have determined the molecular structure of a gut protein that helps us absorb many drugs. This could help to develop drugs that reach target tissues more efficiently.
Molecular & Computational biology
Nov 3, 2021
0
70
