For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require ...
Biochemistry
Dec 28, 2023
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203
A team of Michigan State University scientists has genetically sequenced two species of poisonous mushrooms, discovering that they can theoretically produce billions of compounds through one molecular assembly line. This ...
Biotechnology
Jan 24, 2017
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650
Swiss scientists have developed a new amino acid that can be used to modify the 3-D structure of therapeutic peptides. Insertion of the amino acid into bioactive peptides enhanced their binding affinity up to 40-fold. Peptides ...
Biochemistry
Aug 31, 2014
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2
(PhysOrg.com) -- Many futurists envision a world in which polymer membranes with molecular-sized channels are used to capture carbon, produce solar-based fuels, or desalinating sea water, among many other functions. This ...
Nanomaterials
Jan 11, 2011
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0
Take two poisonous mushrooms, and call me in the morning. While no doctor would ever write this prescription, toxic fungi may hold the secrets to tackling deadly diseases.
Biochemistry
Dec 4, 2014
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0
University of Michigan researchers are celebrating their discovery of a new plant biochemistry and its unusual ability to form cyclic peptides—molecules that hold promise in pharmaceuticals as they can bind to challenging ...
Biochemistry
Feb 14, 2024
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102
Researchers have created tiny protein tubes named after the Roman god Janus which may offer a new way to accurately channel drugs into the body's cells.
Nanomaterials
Nov 14, 2013
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0
A new paper published in Nature Communications presents research on unique peptides with anti-cancer potential.
Biochemistry
Nov 14, 2022
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283
Whitehead Institute scientists have developed a rapid, inexpensive drug-screening method that could be used to target diseases that until now have stymied drug developers, such as Parkinson's disease. This technique uses ...
Biochemistry
Jul 13, 2009
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0
(PhysOrg.com) -- Researchers outline today a new approach in the potential development of drugs to counter a cellular defect that triggers Parkinson’s and other diseases.
Biochemistry
Jul 14, 2009
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