News tagged with channel protein
Unusual protein helps regulate key cell communication pathway
Charged atoms, or ions, move through tiny pores, or channels, embedded in cell membranes, generating the electrical signals that allow cells to communicate with one another. In new research, scientists have ...
Apr 23, 2012 |
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Molding the business end of neurotoxins
For snakes, spiders, and other venomous creatures, the "business end," or active part, of a toxin is the area on the surface of a protein that is most likely to undergo rapid evolution in response to environmental constraints, ...
Feb 23, 2012 |
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Gene discovery explains how fruit flies retreat from heat
A discovery in fruit flies may be able to tell us more about how animals, including humans, sense potentially dangerous discomforts.
Dec 15, 2011 |
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Study shows Alzheimer's disease-related peptides form toxic calcium channels in the plasma membrane
Alzheimer's disease is triggered by the inappropriate processing of amyloid precursor protein to generate excess amounts of short peptide fragments called A-beta. For many years, the neurodegeneration associated with Alzheimer's ...
Oct 24, 2011 |
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Cell's power generator depends on long-sought protein: 50-year search for calcium channel ends
(PhysOrg.com) -- Mitochondria, those battery-pack organelles that fuel the energy of almost every living cell, have an insatiable appetite for calcium. Whether in a dish or a living organism, the mitochondria ...
Jun 19, 2011 |
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Researchers find new 'molecular motors' that bacteria use to transport proteins
(PhysOrg.com) -- Joshua Shaevitz, an assistant professor from the Department of Physics and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, along with Mingzhai Sun, a postdoctoral associate at ...
Jun 13, 2011 |
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Small change makes a big difference for ion channels
Using a high-resolution single-molecule study technique, University of Illinois researchers have seen the very subtle differences between two branches of an important family of neurotransmitter-gated ion channels.
Jun 02, 2011 |
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Researchers get a first look at the mechanics of membrane proteins
In two new studies, researchers provide the first detailed view of the elaborate chemical and mechanical interactions that allow the ribosome – the cell's protein-building machinery – to insert a ...
Apr 17, 2011 |
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Potassium channel gene modifies risk for epilepsy
Vanderbilt University researchers have identified a new gene that can influence a person's risk for developing epilepsy. The findings, reported in the March 29 Proceedings of the National Academy of Sciences, could improv ...
Apr 04, 2011 |
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Scientists crack molecular code regulating neuronal excitability
A key question in protein biochemistry is how proteins recognize "correct" interaction partners in a sea of cellular factors. Nowhere is that more critical to know than in the brain, where interactions governing ...
Medicine & Health / Medical research
Mar 22, 2011 |
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New genetic deafness syndrome identified
Ten years ago, scientists seeking to understand how a certain type of feature on a cell called an L-type calcium channel worked created a knockout mouse missing both copies of the CACNA1D gene.
Mar 09, 2011 |
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Unearthing a pathway to brain damage
Neuroscientists have long suspected that abnormal calcium signaling and accumulation of misfolded proteins cause an intracellular membrane-bound organelle called the endoplasmic reticulum (ER) to trigger the ...
Medicine & Health / Neuroscience
Feb 25, 2011 |
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Process leading to protein diversity in cells important for proper neuron firing
(PhysOrg.com) -- Researchers at the University of Pennsylvania School of Medicine have documented a novel form of splicing in the cytoplasm of a nerve cell, which dictates a special form of a potassium channel ...
Medicine & Health / Medical research
Nov 17, 2010 |
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Protein provides link between calcium signaling in excitable and non-excitable cells
A calcium-sensing protein, STIM1, known to activate store-operated calcium channels has been found to also inhibit voltage-operated calcium channels, according to researchers at Temple University.
Medicine & Health / Medical research
Oct 01, 2010 |
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Back to the future for flu fighters
(PhysOrg.com) -- Australian National University researchers have breathed new life into an old protein drug target in a discovery that could open the door to a new range of drugs to combat influenza.
Medicine & Health / Medical research
Jul 20, 2010 |
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