Another step toward synthetic cells

Building functional synthetic cells from the bottom-up is an ongoing effort of scientists around the globe. Their use in studying cellular mechanisms in a highly controlled and pre-defined setting creates great value for ...

Scientists unravel mechanism for melting of DNA double helix

Researchers at the Francis Crick Institute have uncovered how the double helix structure of DNA is opened to allow DNA replication. The work could lead to further studies to better understand this process including how it ...

DNA nanostructures for targeting cellular surface receptors

A broad subset of parameters, which include cell signaling modulation and receptor binding efficiency, can be explored using programmable DNA nanostructures. Glenn Cremers shows how these structures can uncover important ...

DNA replication under the microscope

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

A bacterial toxin that acts as a mediator rather than a killer

Traditionally, bacterial toxins have been seen as killers of target cells. But is there more than meets the eye? UmeƄ University Professor Teresa Frisan and her team have discovered that toxin-host interactions are more ...

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