Protein filament systems within cells are subject to constant reorganization, which is in part mediated by the actions of motor proteins. LMU researchers have now shown that motor-driven movements can propagate through such ...
Molecular & Computational biology
Jan 9, 2020
0
3
Researchers at the Biozentrum of the University of Basel have demonstrated how bacteria coordinate cell division with the replication of their genetic material. In an interdisciplinary study they explain why the current concept ...
Cell & Microbiology
Dec 30, 2019
1
10
DNA replication is a tightly regulated process that ensures the precise duplication of the genome during cell proliferation. Replication origins determine where replication starts on the genome and regulate the whole genome ...
Molecular & Computational biology
Dec 27, 2019
0
221
Researchers in China have discovered how a Zika virus protein reshapes its host cell to aid viral replication. The study, which will be published December 23 in the Journal of Cell Biology, reveals that the viral protein ...
Cell & Microbiology
Dec 23, 2019
1
35
Two research teams led by Professors Brian Luke and Helle Ulrich at the Institute of Molecular Biology have deciphered how two enzymes, RNase H2 and RNase H1, are coordinated to remove RNA-DNA hybrid structures from chromosomes. ...
Molecular & Computational biology
Nov 27, 2019
1
4
The final stage of DNA replication—"termination"—occurs when two DNA copy machines advance upon each other and unwind the final stretch of DNA. This process occurs about 60,000 times per human cell cycle and is crucial ...
Cell & Microbiology
Oct 28, 2019
0
11
The molecules of life are twisted. But how those familiar strands in DNA's double helix manage to replicate without being tangled up has been hard to decipher. A new perspective from Cornell physicists is helping unravel ...
Molecular & Computational biology
Oct 17, 2019
0
76
The human genome is made up of 46 chromosomes, each of which has a length of about 100 to 200 million base pairs, the building blocks of the DNA double helix. Even during interphase, the period in between the cell division ...
Biotechnology
Oct 9, 2019
0
43
Maintenance of genome integrity—and prevention of diseases such as cancer—requires complete and faithful replication of the genome every cell division cycle.
Biotechnology
Oct 4, 2019
0
11
Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect. The ...
Cell & Microbiology
Aug 29, 2019
0
452
