Related topics: stem cells · transcription factors

How a single molecule turns one immune cell into another

All it takes is one molecule to reprogram an antibody-producing B cell into a scavenging macrophage. This transformation is possible, new evidence shows, because the molecule (C/EBPa, a transcription factor) "short-circuits" ...

Researchers reveal how cells rewrite their fate

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona and the Max Delbrück Center for Molecular Medicine in the Helmholtz Association in Berlin have revealed how cells accelerate changes to their identity, ...

How time affects the fate of stem cells

How do temporal variations in protein concentrations affect biology? It's a question that biologists have only recently begun to address, and the findings are increasingly showing that random temporal changes in the amount ...

Novel epigenetic patterns involved in cell fate regulation

(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) publish exciting new results on the regulation of cell fate in the scientific journal Nature. They identified novel epigenetic ...

Embryo's early development revealed in a dish

During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet of cells known as the ectoderm. While there have been extensive studies of how this sheet forms all these ...

In directing stem cells, study shows context matters

Figuring out how blank slate stem cells decide which kind of cell they want to be when they grow up—a muscle cell, a bone cell, a neuron—has been no small task for science.

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