Expanding the optogenetics toolkit

Controlling individual brain cells using light-sensitive proteins has proven to be a powerful tool for probing the brain's complexities. As this branch of neuroscience has expanded, so has the demand for a diverse palette ...

Team simulates how Alzheimer's disease spreads through the brain

For the first time, scientists have developed a computer simulation of how clumps of defective proteins in neurodegenerative diseases like Alzheimer's spread through the brain, much of the time in stealth mode, over as long ...

Methyl marks on RNA discovered to be key to brain cell connections

Methyl chemical groups dot lengths of DNA, helping to control when certain genes are accessible by a cell. In new research, UCLA scientists have shown that at the connections between brain cells—which often are located ...

Drug makes rats less likely to imbibe alcohol

Alcohol use disorders can have devastating effects on a person's health, relationships and finances. Yet for some, the feeling they get when taking a drink temporarily outweighs these other concerns. Now, researchers have ...

The secret sulfate code that lets the bad Tau in

Vampires can turn humans into vampires, but to enter a human's house, they must be invited in. Researchers at the UT Southwestern Medical Center, writing in the Journal of Biological Chemistry, have uncovered details of how ...

Teaching a machine to spot a crystal

Protein crystals don't usually display the glitz and glam of gemstones. But no matter their looks, each and every one is precious to scientists.

Flow of cerebrospinal fluid regulates division

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory. In a paper scientists have discovered that the flow of cerebrospinal fluid is a key signal for neural ...

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