The molecular tool CRISPR-Cas9 can be used to treat inherited blood disorders, but this may cause unintended genetic alterations. A team led by MDC researchers Klaus Rajewsky and Van Trung Chu has now presented an approach ...
Biotechnology
Jun 23, 2022
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37
This week 20 women are tucking themselves in a waterbed for five days as part of a dry immersion study to recreate some of the effects of spaceflight on the body. The campaign kicked off yesterday with the first two subjects ...
Space Exploration
Sep 24, 2021
1
26
The organization of the human genome relies on physics of different states of matter—such as liquid and solid—a team of scientists has discovered. The findings, which reveal how the physical nature of the genome changes ...
General Physics
Jun 2, 2021
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24
Researchers have discovered a new set of signals that cells send and receive to prompt one type of fat cell to convert fat into heat. The signaling pathway, discovered in mice, has potential implications for activating this ...
Cell & Microbiology
Jun 12, 2020
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215
A key epigenetic mark can block the binding of an important gene regulatory protein, and therefore prohibit the gene from being turned off, a new UNSW study in CRISPR-modified mice—published this month in Nature Communications—has ...
Biotechnology
May 25, 2020
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380
A protein known to help cells defend against infection also regulates the form and function of mitochondria, according to a new paper in Nature Communications.
Cell & Microbiology
Mar 3, 2020
0
501
Scientists at Fred Hutchinson Cancer Research Center took a step toward making gene therapy more practical by simplifying the way gene-editing instructions are delivered to cells. Using a gold nanoparticle instead of an inactivated ...
Materials Science
May 27, 2019
3
193
Researchers at the University of Helsinki uncovered the mechanisms for a novel cellular stress response arising from the toxicity of newly synthesized proteins. Activation of the stress response is at the epicentre of the ...
Cell & Microbiology
Feb 22, 2019
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2
Cells communicate by sending little fat balls to one another. Wouter Roos, professor of Molecular Biophysics at the Rijksuniversiteit Groningen, together with colleagues from Amsterdam and Utrecht, is the first to describe ...
Cell & Microbiology
Nov 26, 2018
0
4
If we really want to know how our body's cells work—or don't work, in the case of disease—we might need to look beyond their genes and even beyond the proteins they are made of. We may need to start going through the ...
Biotechnology
Oct 22, 2018
0
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