(Phys.org) —While the natural world is replete with compounds that form the basis of many disease-fighting pharmaceuticals, it is also the case that humans and other mammals produce their own host-defense peptide-derived ...
When someone becomes infected with the novel coronavirus SARS-CoV-2, the pathogen proliferates rapidly in the cells of the infected person. To do so, the virus has to multiply its genetic material, which consists of a single ...
Cell & Microbiology
Apr 28, 2020
6
501
DNA is often referred to as the blueprint for life, however scientists have for the first time discovered a microbe that uses two different translations of the DNA code at random. This unexpected finding breaks what was thought ...
Biotechnology
Jun 14, 2018
3
570
(PhysOrg.com) -- Diabetes is the most prevalent metabolic disease in developed countries and one that engenders - in addition to its high fatality - enormous health care costs. The physiological meaning of the ‘feel-good’ ...
Biochemistry
Oct 28, 2009
0
1
Johns Hopkins Medicine scientists report they have probed the atomic structure of proteins to add to evidence that the wobbles, shakes and quivers of proteins play a critical role in their ability to function. The findings ...
Molecular & Computational biology
Jul 15, 2022
0
1201
When proteins get "out of shape", the consequences can be fatal. They lose their function and in some cases form insoluble, toxic clumps that damage other cells and can cause severe diseases such as Alzheimer's or Parkinson's. ...
Biochemistry
Feb 11, 2013
0
0
Cancer cells are more dependent on a cellular garbage disposal unit—the proteasome—than healthy cells, and cancer therapies take advantage of this dependency. Scientists at EMBL and MPI determined the proteasome's 3D ...
Biochemistry
Aug 4, 2016
0
872
Proteins are essential for every living cell and responsible for many fundamental processes. In particular, they are required as bio-catalysts in metabolism and for signaling inside the cell and between cells. Many diseases ...
Biochemistry
Sep 19, 2019
0
164
Holger Stark from the Max Planck Institute for Biophysical Chemistry in Göttingen and his team have broken a crucial resolution barrier in cryo electron microscopy. For the first time, his group succeeded in observing individual ...
General Physics
Oct 22, 2020
0
146
Brain cells manufacture proteins in every corner, including their long branches. Neurons missing this ability cause severe neurological disorders like disability and epilepsy. The groups of Marino Zerial, Max Planck Institute ...
Cell & Microbiology
Jun 2, 2023
0
116
