Scientists uncover the nuclear life of actin
A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.
Actin cytonauts at play in the cell
Earliest stages of ear development involve a localized signaling cascade
The proteins associated with driving the cell shape changes that internalize the embryonic inner ear have been identified by Raj Ladher and colleagues from the RIKEN Center for Developmental Biology. "Our ...
Mitosis mystery solved as role of key protein is confirmed
Researchers from Warwick Medical School have discovered the key role of a protein in shutting down endocytosis during mitosis, answering a question that has evaded scientists for half a century.
How do our muscles work? Scientists reveal important new insights into muscle protein
Scientists led by Kristina Djinović-Carugo at the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna have elucidated the molecular structure and regulation ...
Unlocking long-hidden mechanisms of plant cell division
Along with copying and splitting DNA during division, cells must have a way to break safely into two viable daughter cells, a process called cytokinesis. But the molecular basis of how plant cells accomplish ...
Cytoskeletons get a closer look
(Phys.org) —Rice University researchers have developed a theoretical approach to analyze the process by which protein building blocks form the biopolymer skeletons of living cells.
Gravity plays a role in keeping cells small
(Phys.org) —The effects of gravity are relevant when building houses or flying airplanes, but biologists have generally accepted that the average cell is too small for gravity to play a role in how it is ...
Building the ring to divide them all: Septin proteins bundle actin filaments into a ring
Researchers of the FOM Institute AMOLF and from Marseille and Paris have demonstrated that cells require a protein called septin to build a ring of actin filaments. This ring of proteins is crucial to drive ...
Biceps bulge, calves curve, 50-year-old assumptions muscled aside
The basics of how a muscle generates power remain the same: Filaments of myosin tugging on filaments of actin shorten, or contract, the muscle – but the power doesn't just come from what's happening straight ...
Axons' unexpected cytoskeleton structure
(Phys.org)—The plasma membranes that give cells their shapes are typically upheld by linear meshworks of the protein actin. In contrast, Howard Hughes Medical Institute scientists have now discovered that ...
Researchers define role of protein vinculin in cell movement
Researchers at the University of North Carolina and the National Institutes for Health have defined the role of the protein vinculin in enabling cell movement.
Biologists take snapshot of fleeting protein process
Structural biologists from Rice University and Baylor College of Medicine (BCM) have captured the first three-dimensional crystalline snapshot of a critical but fleeting process that takes place thousands ...
Researchers uncover secrets of internal cell fine-tuning
New research from scientists at the University of Kent has shown for the first time how the structures inside cells are regulated – a breakthrough that could have a major impact on cancer therapy development.