Rockefeller University

Laminin builds the neuromuscular synapse

Like a plug and a socket, a nerve and a muscle fiber mesh at the neuromuscular junction. New work by Nishimune et al published in the Journal of Cell Biology reveals that an extracellular matrix protein called laminin shapes ...

Sep 15, 2008
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Structure of a virulent pathogen revealed

(PhysOrg.com) -- Like high-profile politicians, pathogenic bacteria dispatch advance teams to make way for their arrival. But these bacterial agents don’t just secure a safe passage, as a Secret Service ...

Dec 04, 2008
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FHL1 helps build muscle mass

Cowling et al. report how to build muscle mass with FHL1. The protein partners with and activates the transcription factor, NFATc1. Encouraging this partnership might provide a possible treatment for muscle ...

Dec 15, 2008
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How Toxoplasma gondii gets noticed

Researchers provide insight into how Toxoplasma gondii, a common parasite of people and other animals, triggers an immune response in its host. The report will appear online on January 19th in The Journal of Experimental Medicine. ...

Jan 19, 2009
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Fibroblasts invade at a snail's pace

A transcription factor known to drive the formation of fibroblasts during development also promotes their ability to invade and remodel surrounding tissues, report Rowe et al. in the February 9, 2009 issue ...

Feb 02, 2009
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Researchers unveil new monkey model for HIV

By altering just one gene in HIV-1, scientists have succeeded in infecting pig-tailed macaque monkeys with a human version of the virus that has until now been impossible to study directly in animals. The new strain of HIV ...

Mar 02, 2009
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New protein identified in bacterial arsenal

(PhysOrg.com) -- Nearly a billion years ago, bacteria evolved an insidious means of infecting their hosts — a syringe-like mechanism able to inject cells with stealthy hijacker molecules. These molecules, ...

Mar 03, 2009
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Lipid droplets lead a Spartin existence

Spartin, a protein linked to the neuronal disease Troyer syndrome, was thought to function in endocytosis. In the March 23, 2009 issue of the Journal of Cell Biology, Eastman et al. identify an unexpected role f ...

Mar 23, 2009
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