Rockefeller University

FHL1 helps build muscle mass

Cowling et al. report how to build muscle mass with FHL1. The protein partners with and activates the transcription factor, NFATc1. Encouraging this partnership might provide a possible treatment for muscle ...

Dec 15, 2008
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How Toxoplasma gondii gets noticed

Researchers provide insight into how Toxoplasma gondii, a common parasite of people and other animals, triggers an immune response in its host. The report will appear online on January 19th in The Journal of Experimental Medicine. ...

Jan 19, 2009
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Fibroblasts invade at a snail's pace

A transcription factor known to drive the formation of fibroblasts during development also promotes their ability to invade and remodel surrounding tissues, report Rowe et al. in the February 9, 2009 issue ...

Feb 02, 2009
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Researchers unveil new monkey model for HIV

By altering just one gene in HIV-1, scientists have succeeded in infecting pig-tailed macaque monkeys with a human version of the virus that has until now been impossible to study directly in animals. The new strain of HIV ...

Mar 02, 2009
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New protein identified in bacterial arsenal

(PhysOrg.com) -- Nearly a billion years ago, bacteria evolved an insidious means of infecting their hosts — a syringe-like mechanism able to inject cells with stealthy hijacker molecules. These molecules, ...

Mar 03, 2009
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Lipid droplets lead a Spartin existence

Spartin, a protein linked to the neuronal disease Troyer syndrome, was thought to function in endocytosis. In the March 23, 2009 issue of the Journal of Cell Biology, Eastman et al. identify an unexpected role f ...

Mar 23, 2009
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Heart saves muscle

A heart muscle protein can replace its missing skeletal muscle counterpart to give mice with myopathy a long and active life, show Nowak et al. The findings will be published online on Monday, May 25, 2009 ...

May 25, 2009
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To spread, skin cancer attacks immune dendritic cells

(PhysOrg.com) -- Dendritic cells are the sentinels of the immune system. When they’re alert and on guard, they will marshal the body’s immunosoldiers, T cells, to battle at the sight of harmful pathogens. But some diseases, ...

May 27, 2009
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'Misreading' of histone code linked to human cancer

(PhysOrg.com) -- The development of blood from stem cell to fully formed blood cell follows a genetically determined program. When it works properly, blood formation stops when it reaches maturity. But when it doesn’t, ...

Jun 01, 2009
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