Rockefeller University

What makes an axon an axon?

Inside every axon is a dendrite waiting to get out. Hedstrom et al. converted mature axons into dendrites by banishing a protein crucial for neuron development. The results suggest that this transformation could occur after ...

Nov 10, 2008
4.5 / 5 (2) 1

Turn back, wayward axon

To a growing axon, the protein RGMa is a "Wrong Way" sign, alerting it to head in another direction. As Hata et al. demonstrate in the March 9, 2009 issue of the Journal of Cell Biology, translating that s ...

Mar 09, 2009
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'Birth control' for centrioles

Like DNA, centrioles need to duplicate only once per cell cycle. Rogers et al. uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that ...

Jan 26, 2009
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Immune sensors suppress colitis-associated cancer

Particular components of inflammasomes -- protein complexes needed for generating immune responses to pathogens and cellular damage—lessen the severity of colitis and colitis-associated colon cancer in mice, according to ...

Apr 12, 2010
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T cell protein boosts learning

Stress, sickness and depression can generate inflammation in the brain, which is detrimental to learning. According to a new study that will appear online on May 3rd in the Journal of Experimental Medicine, T cells level ...

May 03, 2010
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